Enantioselective synthesis of both enantiomers of dimethyl cis-(4-acetoxycyclopent-2-enyl)malonate, key intermediates for epijasmonate.
نویسندگان
چکیده
Both enantiomers (3 and 4) of dimethyl cis-(4-acetoxycyclopent-2-enyl)malonate (3), known intermediates for the synthesis of epijasmonate, were prepared in an enantio-enriched form from common starting material 2 based on desymmetrization of the meso-character by palladium-catalyzed asymmetric allylic alkylation.
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عنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 66 3 شماره
صفحات -
تاریخ انتشار 2002